Pharmacy PEBC Practice Exam 2025 – 400 Free Practice Questions to Pass the Exam

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How is an antagonist drug defined?

A drug that enhances receptor activity

A drug that binds to a receptor and inhibits its activity

An antagonist drug is specifically defined as a substance that binds to a receptor but does not activate it, thereby inhibiting or blocking the receptor's activity. This characteristic differentiates antagonists from agonists, which enhance or activate receptor activity. For example, when an antagonist attaches to a receptor site, it prevents other molecules (like neurotransmitters or hormones) from binding to that receptor and eliciting a response. This inhibition can have various therapeutic applications, such as reducing symptoms in certain medical conditions by preventing overactivity of specific receptor pathways.

Understanding this concept is crucial in pharmacology, as using antagonists effectively can influence therapeutic outcomes in the treatment of diseases, such as hypertension or anxiety disorders.

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A drug that has no effect on receptor activity

A drug that activates multiple receptors simultaneously

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